Article
Identification of a new target of miR-16, Vacuolar Protein Sorting 4a.
PloS one - 1 Jan 2014
Adhikari Neeta, Guan Weihua, Capaldo Brian, Mackey Aaron J, Carlson Marjorie, Ramakrishnan Sundaram, Walek Dinesha, Gupta Manu, Mitchell Adam, Eckman Peter, John Ranjit, Ashley Euan, Barton Paul J, Hall Jennifer L
Abstract excerpt
RATIONALE: The rationale was to utilize a bioinformatics approach to identify miRNA binding sites in genes with single nucleotide mutations (SNPs) to discover pathways in heart failure (HF). OBJECTIVE: The objective was to focus on the genes containing miRNA binding sites with miRNAs that were significantly altered in end-stage HF and in response to a left ventricular assist device (LVAD). METHODS AND RESULTS:...
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