Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The haplotype of the growth-differentiation factor 15 gene is associated with left ventricular hypertrophy in human essential hypertension.

Clinical science (London, England : 1979) - 19 Oct 2009

Wang Xiaojian, Yang Xu, Sun Kai, Chen Jingzhou, Song Xiaodong, Wang Hu, Liu Zhe, Wang Changxin, Zhang Channa, Hui Rutai

Abstract excerpt

GDF15 (growth-differentiation factor 15) is a novel antihypertrophic factor which is induced in the heart in response to pressure overload and plays an important regulatory role in the process of hypertrophy. In the present study, we have investigated the relationship between GDF15 gene variants and left ventricular hypertrophy in human essential hypertension. A community-based hypertensive population sample of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cross-Sectional Studies
Share to Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Hypertrophy, Left Ventricular

Share to Promoter Regions, Genetic

Share to Transfection

Share to Ultrasonography

Share to Ventricular Remodeling

Source

Identifiers

PMID: 19505289
DOI: 10.1042/CS20080637

Genes

GDF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The haplotype of the growth-differentiation factor 15 gene is associated with left ventricular hypertrophy in human essential hypertension.PMID 19505289Read ↗

Clinical and genetic correlates of growth differentiation factor 15 in the community.Semantic proximity Read ↗

Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humansSemantic proximity Read ↗

Integrated Analyses of Growth Differentiation Factor-15 Concentration and Cardiometabolic Diseases in HumansSemantic proximity Read ↗

Functional characterization of the GWAS lead SNP rs888663 and effects of GDF15 SNPs on GDF15 levels in gestational hypertension and preeclampsia.Semantic proximity Read ↗

Study of the association between growth differentiation factor 15 gene polymorphism and coronary artery disease in a Chinese population.Semantic proximity Read ↗

The impact of growth differentiation factor 15 on the risk of cardiovascular diseases: two-sample Mendelian randomization study.Semantic proximity Read ↗

The impact of growth differentiation factor 15 on the risk of cardiovascular diseases: two-sample Mendelian randomization studySemantic proximity Read ↗

The rs1058587 of growth differentiation factor 15 increased the development and mortality risk of end-stage renal diseaseSemantic proximity Read ↗

GDF-15 as a Biomarker in Cardiovascular DiseaseSemantic proximity Read ↗

Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts.Semantic proximity Read ↗

Kruppel-Like Factor 15 Is Critical for the Development of Left Ventricular Hypertrophy.Semantic proximity Read ↗

The impact of GDF-15, a biomarker for metformin, on the risk of coronary artery disease, breast and colorectal cancer, and type 2 diabetes and metabolic traits: a Mendelian randomisation studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.