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Article

Human genetic evidence for involvement of CD137 in atherosclerosis.

Molecular medicine (Cambridge, Mass.) - 14 Oct 2014

Söderström Leif Å, Gertow Karl, Folkersen Lasse, Sabater-Lleal Maria, Sundman Eva, Sheikine Yuri, Goel Anuj, Baldassarre Damiano, Humphries Steve E, de Faire Ulf, Watkins Hugh, Tremoli Elena, Veglia Fabrizio, Hamsten Anders, Hansson Göran K, Olofsson Peder S

Abstract excerpt

Atherosclerosis is an inflammatory disease and the main cause of cardiovascular disease. Inflammation promotes plaque instability and clinical disease, such as myocardial infarction, stroke and peripheral vascular disease. Subclinical atherosclerosis begins with thickening of the arterial intimal layer, and increased intima-media thickness (IMT) in the carotid artery is a widely used measurement of subclinical...

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Identifiers

PMID: 25032953
DOI: 10.2119/molmed.2014.00004
PMCID: PMC4212009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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