Article
A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE Genetics Study.
European heart journal - 1 May 2010
Buysschaert Ian, Carruthers Kathryn F, Dunbar Donald R, Peuteman Gilian, Rietzschel Ernst, Belmans Ann, Hedley Ann, De Meyer Tim, Budaj Andrzej, Van de Werf Frans, Lambrechts Diether, Fox Keith A A
Abstract excerpt
AIMS: Recent genetic studies identified the rs1333049 variant on chromosome 9p21 as a major susceptibility locus for coronary artery disease and myocardial infarction (MI). Here, we evaluated whether this variant also contributes to recurrent MI or cardiac death following an acute coronary syndrome (ACS). METHODS AND RESULTS: A total of 3247 patients with ACS enrolled in the Global Registry of Acute Coronary...
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