Article
Genetic variants of interleukin 17A are functionally associated with increased risk of age-related macular degeneration.
Inflammation - 1 Apr 2015
Zhang Shaoru, Liu Yonghua, Lu Shilin, Cai Xinmeng
Abstract excerpt
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in elderly populations worldwide. Inflammation, among many factors, has been suggested to play an important role in AMD pathogenesis. Interleukin 17 (IL-17) is a proinflammatory cytokine that has been implicated in the pathogenesis of various autoimmune diseases. In the current study, we examined two single nucleotide...
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