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Article

Complement component C5a Promotes Expression of IL-22 and IL-17 from Human T cells and its Implication in Age-related Macular Degeneration

15 Jul 2011

Abstract excerpt

BACKGROUND: Age related macular degeneration (AMD) is the leading cause of irreversible blindness in elderly populations worldwide. Inflammation, among many factors, has been suggested to play an important role in AMD pathogenesis. Recent studies have demonstrated a strong genetic association between AMD and complement factor H (CFH), the down-regulatory factor of complement activation. Elevated levels of...

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Complement system in diseases
Ocular Diseases and Behçet’s Syndrome
Retinal Diseases and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21762495
DOI: 10.1186/1479-5876-9-111

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