Article
Effects of transgenic overproduction of CRH on anxiety-like behaviour.
The European journal of neuroscience - 1 Jun 2002
van Gaalen Marcel M, Stenzel-Poore Mary P, Holsboer Florian, Steckler Thomas
Abstract excerpt
Central administration of corticotropin-releasing hormone increases anxiety-like behaviour and arousal in rodents, and increased anxiety-like behaviour has been shown in mice overproducing corticotropin-releasing hormone on an elevated plus maze and in a dark-light emergence task. However, evidence is accumulating that measures obtained from different anxiety tasks may reflect different aspects of anxiety-like...
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