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Article

Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A.

Journal of proteome research - 1 Aug 2014

Foster Matthew W, Thompson J Will, Ledford Julie G, Dubois Laura G, Hollingsworth John W, Francisco Dave, Tanyaratsrisakul Sasipa, Voelker Dennis R, Kraft Monica, Moseley M Arthur, Foster W Michael

Abstract excerpt

Pulmonary surfactant protein A (SP-A), a heterooligomer of SP-A1 and SP-A2, is an important regulator of innate immunity of the lung. Nonsynonymous single nucleotide variants of SP-A have been linked to respiratory diseases, but the expressed repertoire of SP-A protein in human airway has not been investigated. Here, we used parallel trypsin and Glu-C digestion, followed by LC-MS/MS, to obtain sequence coverage...

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PMID: 25025725
DOI: 10.1021/pr500307f
PMCID: PMC4123939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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