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Article

Mutations of C-reactive protein (CRP) -286 SNP, APC and p53 in colorectal cancer: implication for a CRP-Wnt crosstalk.

PloS one - 1 Jan 2014

Su Hai-Xiang, Zhou Hai-Hong, Wang Ming-Yu, Cheng Jin, Zhang Shi-Chao, Hui Feng, Chen Xue-Zhong, Liu Shan-Hui, Liu Qin-Jiang, Zhu Zi-Jiang, Hu Qing-Rong, Wu Yi, Ji Shang-Rong

Abstract excerpt

C-reactive protein (CRP) is an established marker of inflammation with pattern-recognition receptor-like activities. Despite the close association of the serum level of CRP with the risk and prognosis of several types of cancer, it remains elusive whether CRP contributes directly to tumorigenesis or just represents a bystander marker. We have recently identified recurrent mutations at the SNP position -286...

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Share to Polymorphism, Single Nucleotide
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 25025473
DOI: 10.1371/journal.pone.0102418
PMCID: PMC4099363

Genes

CRP
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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