Article
C-reactive protein levels, variation in the C-reactive protein gene, and cancer risk: the Rotterdam Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Nov 2006
Siemes Claire, Visser Loes E, Coebergh Jan-Willem W, Splinter Ted A W, Witteman Jacqueline C M, Uitterlinden André G, Hofman Albert, Pols Huibert A P, Stricker Bruno H Ch
Abstract excerpt
PURPOSE: It remains unclear if inflammation itself may induce cancer, if inflammation is a result of tumor growth, or a combination of both exists. The aim of this study was to examine whether C-reactive protein (CRP) levels and CRP gene variations were associated with an altered risk of colorectal, lung, breast, or prostate cancer. PATIENTS AND METHODS: A total of 7,017 participants age > or = 55 years from the...
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