A Functional Genetic Variant at the C-Reactive Protein Promoter (rs3091244) Is Not Associated With Cancer Risk in a Chinese Population.

doi:10.3389/fimmu.2020.00926

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A Functional Genetic Variant at the C-Reactive Protein Promoter (rs3091244) Is Not Associated With Cancer Risk in a Chinese Population.

Frontiers in immunology - 1 Jan 2020

Wang Ming-Yu, Zhou Hai-Hong, Zhang Chun-Miao, Su Hai-Xiang, Li Shuo-Lei, Ji Shang-Rong, Liu Enqi, Wu Yi

Abstract excerpt

Background: The association of genetically elevated levels of circulating C-reactive protein (CRP) with cancer risk has been extensively investigated in European populations; however, there are conflicting conclusions. The tri-allelic rs3091244 is a functionally validated genetic variant, and its allelic frequencies differ significantly between European and Asian populations. Here, we examined the association of...

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PMID: 32477370
DOI: 10.3389/fimmu.2020.00926
PMCID: PMC7240006

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