Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of the TCR Repertoire as a Predictive and Prognostic Biomarker in Cancer: Diversity or Clonality?

31 Mar 2022

Abstract excerpt

T cells play a vital role in the anti-tumoural response, and the presence of tumour-infiltrating lymphocytes has shown to be directly correlated with a good prognosis in several cancer types. Nevertheless, some patients presenting tumour-infiltrating lymphocytes do not have favourable outcomes. The TCR determines the specificities of T cells, so the analysis of the TCR repertoire has been recently considered to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35406543
DOI: 10.3390/cancers14071771

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of the TCR Repertoire as a Predictive and Prognostic Biomarker in Cancer: Diversity or Clonality?PMID 35406543Read ↗

T-cell repertoire diversity: friend or foe for protective antitumor response?Semantic proximity Read ↗

Human TCR repertoire in cancerSemantic proximity Read ↗

T-cell receptor diversity as a prognostic biomarker in melanoma patients.Semantic proximity Read ↗

Characteristics of profiling the peripheral blood T‐cell receptor repertoire in patients with diffuse large B-cell lymphomaSemantic proximity Read ↗

T-Cell Receptor Repertoire Sequencing in the Era of Cancer ImmunotherapySemantic proximity Read ↗

Tissue and Peripheral T-cell Repertoire Predicts Immunotherapy Response and Progression-Free Survival in NSCLC PatientsSemantic proximity Read ↗

TCR Repertoire as a Novel Indicator for Immune Monitoring and Prognosis Assessment of Patients With Cervical CancerSemantic proximity Read ↗

Next‐generation <scp>TCR</scp> sequencing – a tool to understand T‐cell infiltration in human cancersSemantic proximity Read ↗

Comparative Profiling of TCR Repertoires in Extranodal NK/T-Cell Lymphoma and Healthy Individuals Highlights Unique Clonal Expansions and Potential Diagnostic BiomarkersSemantic proximity Read ↗

T-Cell Receptor Repertoire Sequencing and Its Applications: Focus on Infectious Diseases and CancerSemantic proximity Read ↗

Characteristics of profiling the peripheral blood T-cell receptor β-chain repertoire in gastric cancerSemantic proximity Read ↗

TCR Repertoire Analysis by Next Generation Sequencing Allows Complex Differential Diagnosis of T Cell–Related PathologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.