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Article

Variation in Sp1 binding sites correlates with expression of survivin in breast cancer.

Molecular medicine reports - 1 Sept 2014

Xu Qing, Liu Mei, Xu Ningzhi, Zhu Hongxia

Abstract excerpt

Survivin is the smallest member of the inhibitor of apoptosis (IAP) family and is deregulated in breast cancer, where it is associated with a poor overall prognosis. It is well established that survivin overexpression predominately occurs at the transcriptional level. Numerous transcription factors bind to specific sequences in the promoter regions of genes and are involved in transcriptional regulation....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25018047
DOI: 10.3892/mmr.2014.2371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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