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Article

Admixture mapping analysis reveals differential genetic ancestry associated with Chagas disease susceptibility in the Colombian population.

Human molecular genetics - 30 Nov 2021

Casares-Marfil Desiré, Guillen-Guio Beatriz, Lorenzo-Salazar Jose M, Rodríguez-Pérez Héctor, Kerick Martin, Jaimes-Campos Mayra A, Díaz Martha L, Estupiñán Elkyn, Echeverría Luis E, González Clara I, Martín Javier, Flores Carlos, Acosta-Herrera Marialbert

Abstract excerpt

Chagas disease is an infection caused by the parasite Trypanosoma cruzi, endemic in Latino America. Leveraging the three-way admixture between Native American (AMR), European (EUR) and African (AFR) populations in Latin Americans, we aimed to better understand the genetic basis of Chagas disease by performing an admixture mapping study in a Colombian population. A two-stage study was conducted, and subjects were...

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Identifiers

PMID: 34302177
DOI: 10.1093/hmg/ddab213
PMCID: PMC8643504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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