Article
Assessing accuracy of genotype imputation in American Indians.
PloS one - 1 Jan 2014
Malhotra Alka, Kobes Sayuko, Bogardus Clifton, Knowler William C, Baier Leslie J, Hanson Robert L
Abstract excerpt
BACKGROUND: Genotype imputation is commonly used in genetic association studies to test untyped variants using information on linkage disequilibrium (LD) with typed markers. Imputing genotypes requires a suitable reference population in which the LD pattern is known, most often one selected from...
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