Article
Sequencing and expression analyses of the synaptic lipid raft adapter gene PAG1 in schizophrenia.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2015
Balan Shabeesh, Iwayama Yoshimi, Yamada Kazuo, Toyota Tomoko, Ohnishi Tetsuo, Toyoshima Manabu, Shimamoto Chie, Ide Masayuki, Iwata Yasuhide, Suzuki Katsuaki, Kikuchi Mitsuru, Hashimoto Tasuku, Kanahara Nobuhisa, Yoshikawa Takeo, Maekawa Motoko
Abstract excerpt
Disruption of synaptic networks has been advocated in the pathogenesis of psychiatric diseases like schizophrenia. The majority of synaptic proteins involved in neuronal communications are localized in lipid rafts. These rafts form the platform for coordinating neuronal signal transduction, by cl...
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