Article
A family-based association study of PLP1 and schizophrenia.
Neuroscience letters - 3 Mar 2005
Qin Wei, Gao Jianjun, Xing Qinghe, Yang Jiandong, Qian Xueqing, Li Xingwang, Guo Zhongmeng, Chen Helong, Wang Lijun, Huang Xuanyin, Gu Niufan, Feng Guoyin, He Lin
Abstract excerpt
Recently, proteolipid protein 1 (PLP1) has been identified as downregulated in schizophrenia by quantitative PCR and other technologies. In this work we attempted to investigate the role of PLP1 in the etiology of schizophrenia using a family based association study in 487 Chinese Han family trios. The TDT for allelic association demonstrated that, in male, a weak association was detected in SNP rs475827 with...
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