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Article

Association of gut commensal translocation with autoantibody production in systemic lupus erythematosus

9 Sept 2024

Abstract excerpt

OBJECTIVE: Bacterial translocation across the gut barrier has been implicated in the pathogenesis of SLE, though the underlying mechanisms remain unclear. This study aimed to investigate the role of translocated bacteria in the context of molecular mimicry by utilizing lupus model mice and blood samples from untreated SLE patients. METHODS: Bacterial translocation was evaluated using nonselective cultured...

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PMID: 39250733
DOI: 10.1093/rheumatology/keae476

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