Article
The transcription factor Fezf2 directs the differentiation of neural stem cells in the subventricular zone toward a cortical phenotype.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 2014
Zuccotti Annalisa, Le Magueresse Corentin, Chen Min, Neitz Angela, Monyer Hannah
Abstract excerpt
Postnatal neurogenesis in mammals is confined to restricted brain regions, including the subventricular zone (SVZ). In rodents, the SVZ is a lifelong source of new neurons fated to migrate to the olfactory bulb (OB), where the majority become GABAergic interneurons. The plastic capacity of neonatal and adult SVZ stem/progenitor cells is still largely unknown. By overexpressing the transcription factor Fezf2, a...
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