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Article

Establishment and characterization of esophageal squamous cell carcinoma patient-derived xenograft mouse models for preclinical drug discovery.

Laboratory investigation; a journal of technical methods and pathology - 1 Aug 2014

Zhang Jingchuan, Jiang Dongxian, Li Xiaojing, Lv Jing, Xie Liang, Zheng Li, Gavine Paul R, Hu Qin, Shi Yuan, Tan Lijie, Ge Di, Xu Songtao, Li Leon, Zhu Lifang, Hou Yingyong, Wang Qun

Abstract excerpt

The purpose of this study was to establish and characterize patient-derived esophageal squamous cell carcinoma xenograft (PDECX) mice for utilization in antitumor drug discovery. A total of 96 esophageal squamous cell carcinoma (ESCC) tissues from Chinese patients were transplanted subcutaneously...

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Source

Identifiers

PMID: 24999713
DOI: 10.1038/labinvest.2014.77

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24999713-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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