Article
Confirmation of the association between LRRK2 R1628P variant and susceptibility to Parkinson's disease in the Thai population.
Parkinsonism & related disorders - 1 Sept 2014
Pulkes Teeratorn, Papsing Chutima, Thakkinstian Ammarin, Pongpakdee Sunsanee, Kulkantrakorn Kongkiat, Hanchaiphiboolkul Suchat, Tiamkao Somsak, Boonkongchuen Pairoj
Abstract excerpt
OBJECTIVE: LRRK2 p.R1628P (c.4883G > C) is associated with Parkinson's disease (PD) in Chinese and Thais. However, some studies in other East Asian ethnic groups did not observe this association. Carriers of p.R1628P are about 3-5% Chinese and Thais. In contrast, Japanese, Koreans and Malays are much less prevalent (0-<1%). The contradictory results may be caused by insufficient sample sizes especially studies in...
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