Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reward dysfunction in major depression: multimodal neuroimaging evidence for refining the melancholic phenotype.

NeuroImage - 1 Nov 2014

Foti Dan, Carlson Joshua M, Sauder Colin L, Proudfit Greg H

Abstract excerpt

Reward dysfunction is thought to play a core role in the pathophysiology of major depressive disorder (MDD). Event-related potential (ERP) and functional magnetic resonance imaging (fMRI) studies have identified reward processing deficits in MDD, but these methods have yet to be applied together in a single MDD sample. We utilized multimodal neuroimaging evidence to examine reward dysfunction in MDD. Further, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Mapping
Share to Depressive Disorder, Major
Share to Electroencephalography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evoked Potentials

Share to Magnetic Resonance Imaging

Share to Multimodal Imaging

Share to Phenotype

Share to Reward

Source

Open in PubMed Open full text

Identifiers

PMID: 24996119
DOI: 10.1016/j.neuroimage.2014.06.058
PMCID: PMC4165813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reward dysfunction in major depression: multimodal neuroimaging evidence for refining the melancholic phenotype.PMID 24996119Read ↗

Distinct neurofunctional alterations during motivational and hedonic processing of natural and monetary rewards in depression – a neuroimaging meta-analysisSemantic proximity Read ↗

Reduced hedonic capacity in major depressive disorder: evidence from a probabilistic reward task.Semantic proximity Read ↗

Investigating functional connectivity differences during food vs. monetary reward processing across appetitive phenotypes of major depressive disorder.Semantic proximity Read ↗

Striatal reactivity to reward under threat-of-shock and working memory load in adults at increased familial risk for major depression: A preliminary study.Semantic proximity Read ↗

Interaction effects of Irritability and Anhedonia on ERP and Time-Frequency Measures of Reward SensitivitySemantic proximity Read ↗

Candidate pathophysiology processes in Fragile-X associated neuropsychiatric disorders: An event-related potential studySemantic proximity Read ↗

Depression Attenuates Caudate and Dorsolateral Prefrontal Cortex Alpha and Beta Power Response to RewardSemantic proximity Read ↗

Interaction effects of Irritability and Anhedonia on ERP and Time-Frequency Measures of Reward SensitivitySemantic proximity Read ↗

Reward Functioning Abnormalities in Adolescents at High Familial Risk for Depressive Disorders.Semantic proximity Read ↗

Altered reward network responses to social touch in major depressionSemantic proximity Read ↗

Toward an objective characterization of an anhedonic phenotype: a signal-detection approach.Semantic proximity Read ↗

An fMRI Phenotype of Reward in Effort Expenditure in the VTA and Dorsal Raphe: A Longitudinal Study of Depression under Escitalopram TreatmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.