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Article

Toward an objective characterization of an anhedonic phenotype: a signal-detection approach.

Biological psychiatry - 15 Feb 2005

Pizzagalli Diego A, Jahn Allison L, O'Shea James P

Abstract excerpt

BACKGROUND: Difficulties in defining and characterizing phenotypes has hindered progress in psychiatric genetics and clinical neuroscience. Decreased approach-related behavior and anhedonia (lack of responsiveness to pleasure) are considered cardinal features of depression, but few studies have used laboratory-based measures to objectively characterize these constructs. METHODS: To assess hedonic capacity in...

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Identifiers

PMID: 15705346
DOI: 10.1016/j.biopsych.2004.11.026
PMCID: PMC2447922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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