Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating functional connectivity differences during food vs. monetary reward processing across appetitive phenotypes of major depressive disorder.

Journal of affective disorders - 15 Nov 2026

Brassard Sarah L, Ahn Hyeon Min, Cerit Hilâl, Hye Taryn, Durham E Leighton, Chang Rose S, Hall Julia, Boukezzi Sarah, Goldstein Jill M, Dillon Daniel G, Pizzagalli Diego A, Holsen Laura M

Abstract excerpt

Reward processing deficits are prominent in major depressive disorder (MDD) and contribute to appetitive phenotypes: hyperphagic (HyperMDD) and hypophagic (HypoMDD). However, few studies have examined neurobiological processes underlying these phenotypes, and whether they stem from aberrant responsivity specific to food or rewards more broadly. This study probed group differences in functional connectivity during...

Topics

Join the communities discussing this publication.

Cues
Food
Hyperphagia
Magnetic Resonance Imaging
Major Depressive Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neural Pathways

Source

Open in PubMed Open full text

Identifiers

PMID: 42431322
DOI: 10.1016/j.jad.2026.122235
PMCID: PMC13455718

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating functional connectivity differences during food vs. monetary reward processing across appetitive phenotypes of major depressive disorder.PMID 42431322Read ↗

Distinct neurofunctional alterations during motivational and hedonic processing of natural and monetary rewards in depression – a neuroimaging meta-analysisSemantic proximity Read ↗

Alterations in resting-state functional activity and connectivity for major depressive disorder appetite and weight disturbance phenotypes.Semantic proximity Read ↗

Neural correlates of reward processing distinguish healthy youth at familial risk for bipolar disorder from youth at familial risk for major depressive disorder.Semantic proximity Read ↗

Transdiagnostic neuroimaging of reward system phenotypes in ADHD and comorbid disorders.Semantic proximity Read ↗

Reward dysfunction in major depression: multimodal neuroimaging evidence for refining the melancholic phenotype.Semantic proximity Read ↗

Anxiety Modulates Reward Circuitry: Altered Cross-Modal Neural Connectivity Revealed by fMRI During Monetary Incentive ProcessingSemantic proximity Read ↗

Dissociable neurofunctional and molecular characterizations of reward and punishment sensitivitySemantic proximity Read ↗

Connectome Gradient Dysfunction in Major Depression and Its Association with Gene Expression ProfilesSemantic proximity Read ↗

Dissociable Neural Connectome Mapping of Reward and Punishment Responsiveness in Young Adults: Associations with Genetic Variability and Neurotransmitter Profiles.Semantic proximity Read ↗

Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depressionSemantic proximity Read ↗

Depression, marijuana use and early-onset marijuana use conferred unique effects on neural connectivity and cognition.Semantic proximity Read ↗

Disorder- and emotional context-specific neurofunctional alterations during inhibitory control in generalized anxiety disorder and major depressive disorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.