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Article

Reward Functioning Abnormalities in Adolescents at High Familial Risk for Depressive Disorders.

Biological psychiatry. Cognitive neuroscience and neuroimaging - 1 Mar 2021

Belleau Emily L, Kremens Rebecca, Ang Yuen-Siang, Pisoni Angela, Bondy Erin, Durham Katherine, Auerbach Randy P, Pizzagalli Diego A

Abstract excerpt

BACKGROUND: A parental history of major depressive disorder (MDD) is an established risk factor for MDD in youth, and clarifying the mechanisms related to familial risk transmission is critical. Aberrant reward processing is a promising biomarker of MDD risk; accordingly, the aim of this study was to test behavioral measures of reward responsiveness and underlying frontostriatal resting activity in healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33160881
DOI: 10.1016/j.bpsc.2020.08.016
PMCID: PMC7936004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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