Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced hedonic capacity in major depressive disorder: evidence from a probabilistic reward task.

Journal of psychiatric research - 1 Nov 2008

Pizzagalli Diego A, Iosifescu Dan, Hallett Lindsay A, Ratner Kyle G, Fava Maurizio

Abstract excerpt

OBJECTIVE: Anhedonia, the lack of reactivity to pleasurable stimuli, is a cardinal feature of depression that has received renewed interest as a potential endophenotype of this debilitating disease. The goal of the present study was to test the hypothesis that individuals with major depression are characterized by blunted reward responsiveness, particularly when anhedonic symptoms are prominent. METHODS: A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Affective Symptoms
Share to Diagnostic and Statistical Manual of Mental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Emotions

Share to Models, Psychological

Share to Psychiatric Status Rating Scales

Share to Reinforcement, Psychology

Share to Reward

Share to Task Performance and Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 18433774
DOI: 10.1016/j.jpsychires.2008.03.001
PMCID: PMC2637997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced hedonic capacity in major depressive disorder: evidence from a probabilistic reward task.PMID 18433774Read ↗

Toward an objective characterization of an anhedonic phenotype: a signal-detection approach.Semantic proximity Read ↗

Untenable Dynamics of Reward Sensitivity in Adolescents with Major Depressive DisorderSemantic proximity Read ↗

Distinct neurofunctional alterations during motivational and hedonic processing of natural and monetary rewards in depression – a neuroimaging meta-analysisSemantic proximity Read ↗

The conceptualization, measurement, and critical appraisal of computational models of anhedonia in depressionSemantic proximity Read ↗

Reward dysfunction in major depression: multimodal neuroimaging evidence for refining the melancholic phenotype.Semantic proximity Read ↗

Computational Phenotyping of Effort-Based Decision Making in Unmedicated Adults With Remitted Depression.Semantic proximity Read ↗

A Neurophysiological Measure of Reward Sensitivity and its Limited Association with Anhedonia in Adolescents and Young AdultsSemantic proximity Read ↗

Striatal reactivity to reward under threat-of-shock and working memory load in adults at increased familial risk for major depression: A preliminary study.Semantic proximity Read ↗

The heritability of hedonic capacity and perceived stress: a twin study evaluation of candidate depressive phenotypes.Semantic proximity Read ↗

Extraversion but not depression predicts reward sensitivity: Revisiting the measurement of anhedonic phenotypes.Semantic proximity Read ↗

Ketamine improves anhedonic phenotypes across species: Translational evidence from the Probabilistic Reward TaskSemantic proximity Read ↗

Reward pursuit during a translational reward task predicts anhedonia reductions following rTMS in patients with major depressive disorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.