Article
Update on iron metabolism and molecular perspective of common genetic and acquired disorder, hemochromatosis.
Critical reviews in oncology/hematology - 1 Jul 2015
Yun Seongseok, Vincelette Nicole D
Abstract excerpt
Iron is an essential component of erythropoiesis and its metabolism is tightly regulated by a variety of internal and external cues including iron storage, tissue hypoxia, inflammation and degree of erythropoiesis. There has been remarkable improvement in our understanding of the molecular mechanisms of iron metabolism past decades. The classical model of iron metabolism with iron response element/iron response...
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