A pilot study evaluating the contribution of SLC19A1 (RFC-1) 80G>a polymorphism to Alzheimer's disease in Italian Caucasians.

doi:10.1155/2014/608104

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A pilot study evaluating the contribution of SLC19A1 (RFC-1) 80G>a polymorphism to Alzheimer's disease in Italian Caucasians.

BioMed research international - 1 Jan 2014

Coppedè Fabio, Tannorella Pierpaola, Tognoni Gloria, Bagnoli Silvia, Bongioanni Paolo, Nacmias Benedetta, Siciliano Gabriele, Sorbi Sandro, Bonuccelli Ubaldo, Migliore Lucia

Abstract excerpt

Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. Polymorphisms of genes involved in folate metabolism have been frequently suggested as risk factors for sporadic AD. A common c.80G>A polymorphism (rs1051266) in the gene coding for the reduced folate carrier (SLC19A1 gene, commonly known as RFC-1 gene) was investigated as AD risk factor in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Alzheimer Disease

Share to Genetic Association Studies

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Reduced Folate Carrier Protein

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 24995314
DOI: 10.1155/2014/608104
PMCID: PMC4068058

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A pilot study evaluating the contribution of SLC19A1 (RFC-1) 80G>a polymorphism to Alzheimer's disease in Italian Caucasians.PMID 24995314Read ↗

Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease.Semantic proximity Read ↗

Serum folic acid and RFC A80G polymorphism in Alzheimer's disease and vascular dementia.Semantic proximity Read ↗

The C677T methylenetetrahydrofolate reductase mutation is not associated with Alzheimer's disease.Semantic proximity Read ↗

Association analysis of CbetaS 844ins68 and MTHFD1 G1958A polymorphisms with Alzheimer's disease in Chinese.Semantic proximity Read ↗

The MTHFR C677T polymorphism contributes to increased risk of Alzheimer's disease: evidence based on 40 case-control studies.Semantic proximity Read ↗

The reduced folate carrier (SLC19A1) c.80G>A polymorphism is associated with red cell folate concentrations among women.Semantic proximity Read ↗

Mutational screening analysis of DHCR24/seladin-1 gene in Italian familial Alzheimer's disease.Semantic proximity Read ↗

RFC1 and non-syndromic cleft lip with or without cleft palate: an association based study in Italy.Semantic proximity Read ↗

MTHFR gene A1298C polymorphism and Alzheimer’s disease susceptibilitySemantic proximity Read ↗

Methylenetetrahydrofolate reductase C667T polymorphism and susceptibility to late-onset Alzheimer's disease in the Italian population.Semantic proximity Read ↗

Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a Chinese population.Semantic proximity Read ↗

Association study to evaluate the serotonin transporter and apolipoprotein E genes in frontotemporal lobar degeneration in Italy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.