Article
Natural selection for the Duffy-null allele in the recently admixed people of Madagascar.
Proceedings. Biological sciences - 22 Aug 2014
Hodgson Jason A, Pickrell Joseph K, Pearson Laurel N, Quillen Ellen E, Prista António, Rocha Jorge, Soodyall Himla, Shriver Mark D, Perry George H
Abstract excerpt
While gene flow between distantly related populations is increasingly recognized as a potentially important source of adaptive genetic variation for humans, fully characterized examples are rare. In addition, the role that natural selection for resistance to vivax malaria may have played in the extreme distribution of the protective Duffy-null allele, which is nearly completely fixed in mainland sub-Saharan...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
