Article
An integrative somatic mutation analysis to identify pathways linked with survival outcomes across 19 cancer types.
Bioinformatics (Oxford, England) - 1 Jun 2016
Park Sunho, Kim Seung-Jun, Yu Donghyeon, Peña-Llopis Samuel, Gao Jianjiong, Park Jin Suk, Chen Beibei, Norris Jessie, Wang Xinlei, Chen Min, Kim Minsoo, Yong Jeongsik, Wardak Zabi, Choe Kevin, Story Michael, Starr Timothy, Cheong Jae-Ho, Hwang Tae Hyun
Abstract excerpt
MOTIVATION: Identification of altered pathways that are clinically relevant across human cancers is a key challenge in cancer genomics. Precise identification and understanding of these altered pathways may provide novel insights into patient stratification, therapeutic strategies and the development of new drugs. However, a challenge remains in accurately identifying pathways altered by somatic mutations across...
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