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Article

Longitudinal changes in glucocorticoid metabolism are associated with later development of adverse metabolic phenotype.

European journal of endocrinology - 1 Oct 2014

Crowley Rachel K, Hughes Beverly, Gray Joanna, McCarthy Theresa, Hughes Susan, Shackleton Cedric H L, Crabtree Nicola, Nightingale Peter, Stewart Paul M, Tomlinson Jeremy W

Abstract excerpt

OBJECTIVE: Dysregulation of enzymes that control local tissue steroid metabolism has been implicated in the pathogenesis of obesity and insulin resistance; however, longitudinal changes in glucocorticoid metabolism have not been investigated. This study was performed to evaluate the role of glucocorticoid metabolism in the development of insulin resistance and obesity and to identify biomarkers for future...

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Identifiers

PMID: 24986533
DOI: 10.1530/EJE-14-0256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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