Article
Dedicated immunosensing of the mouse intestinal epithelium facilitated by a pair of genetically coupled lectin-like receptors.
Mucosal immunology - 1 Mar 2015
Leibelt S, Friede M E, Rohe C, Gütle D, Rutkowski E, Weigert A, Kveberg L, Vaage J T, Hornef M W, Steinle A
Abstract excerpt
The integrity of the intestinal epithelium is constantly surveyed by a peculiar subset of innate-like T lymphocytes embedded in the epithelial cell layer, hence called intestinal intraepithelial lymphocytes (IELs). IELs are thought to act as "first-line" sentinels sensing the state of adjacent ep...
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