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Structural and electrostatic analysis of HLA B-cell epitopes

29 Jun 2014

Abstract excerpt

PURPOSE OF REVIEW: The immunogenic capacity of donor human leukocyte antigen (HLA) to induce humoral immune responses is not an intrinsic property of the mismatched alloantigen but depends on the HLA phenotype of the recipient. In recent years, advances in molecular sequence technology and information from X-ray crystallography have enabled structural comparison of donor and recipient HLA type providing an...

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PMID: 24977436
DOI: 10.1097/mot.0000000000000108

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