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Article

The antibody response to an HLA mismatch: a model for nonself-self discrimination in relation to HLA epitope immunogenicity.

International journal of immunogenetics - 1 Feb 2012

Duquesnoy R J

Abstract excerpt

Antibodies to HLA mismatches are specific for epitopes rather than antigens. HLAMatchmaker considers each HLA antigen as a string of eplets that represent key elements of epitopes. Certain antibodies are specific for single eplets, but recent studies have demonstrated that epitopes defined by eplet pairs always involve one nonself-eplet and a self-eplet shared between the immunizing antigen and the antibody...

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Share to Antibody Formation
Share to Antibody Specificity
Share to Blood Transfusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Rearrangement, B-Lymphocyte

Share to HLA Antigens

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Share to Models, Immunological

Source

Identifiers

PMID: 21981757
DOI: 10.1111/j.1744-313X.2011.01042.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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