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Article

Computational prediction of a putative binding site on drp1: implications for antiparkinsonian therapy.

Journal of chemical information and modeling - 28 Jul 2014

Pradeep Hanumanthappa, Rajanikant G Krishnamurthy

Abstract excerpt

Parkinson's disease is the second most common neurodegenerative disorder, for which no cure or disease-modifying therapies exist. It is evident that mechanisms impairing mitochondrial dynamics will damage cell signaling pathways, leading to neuronal death that manifests as Parkinson's disease. Dynamin related protein1, a highly conserved profission protein that catalyzes the process of mitochondrial fission, is...

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Identifiers

PMID: 24977305
DOI: 10.1021/ci500243h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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