ABCG1 rs57137919G>a polymorphism is functionally associated with varying gene expression and apoptosis of macrophages.

doi:10.1371/journal.pone.0097044

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Article

ABCG1 rs57137919G>a polymorphism is functionally associated with varying gene expression and apoptosis of macrophages.

PloS one - 1 Jan 2014

Liu Fang, Wang Wei, Xu Yan, Wang Yu, Chen Lian-Feng, Fang Quan, Yan Xiao-Wei

Abstract excerpt

ATP-binding cassette transporter G1 (ABCG1) is a transmembrane cholesterol transporter involved in macrophage sterol homeostasis, reverse cholesterol transport (RCT), and atherosclerosis. The role of ABCG1 in atherosclerosis remains controversial, especially in animal models. Our previous study showed that single nucleotide polymorphism rs57137919 (-367G>A) in the ABCG1 promoter region was associated with reduced...

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PMID: 24972087
DOI: 10.1371/journal.pone.0097044
PMCID: PMC4074052

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ABCG1
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