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Article

Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men.

Journal of atherosclerosis and thrombosis - 1 Jun 2009

Furuyama Shoudai, Uehara Yoshinari, Zhang Bo, Baba Yasuhiko, Abe Satomi, Iwamoto Takahiro, Miura Shin-Ichiro, Saku Keijiro

Abstract excerpt

AIM: ATP-binding cassette transporter G1 (ABCG1) is a cholesterol transporter that plays a role in cholesterol efflux in the presence of high-density lipoprotein (HDL). Moreover, HDL-mediated cholesterol efflux is increased in cultured ABCG1 overexpressed cells; however, the physiological roles of ABCG1 and its contribution to atherosclerosis in humans remain unclear. METHODS: The effect of ABCG1 -257T>G mutation...

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Source

Identifiers

PMID: 19556716
DOI: 10.5551/jat.e380

Genes

ABCG1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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