Article
EMMPRIN/CD147 deficiency disturbs ameloblast-odontoblast cross-talk and delays enamel mineralization.
Bone - 1 Sept 2014
Khaddam Mayssam, Huet Eric, Vallée Benoît, Bensidhoum Morad, Le Denmat Dominique, Filatova Anna, Jimenez-Rojo Lucia, Ribes Sandy, Lorenz Georg, Morawietz Maria, Rochefort Gael Y, Kiesow Andreas, Mitsiadis Thimios A, Poliard Anne, Petzold Matthias, Gabison Eric E, Menashi Suzanne, Chaussain Catherine
Abstract excerpt
Tooth development is regulated by a series of reciprocal inductive signaling between the dental epithelium and mesenchyme, which culminates with the formation of dentin and enamel. EMMPRIN/CD147 is an Extracellular Matrix MetalloPRoteinase (MMP) INducer that mediates epithelial-mesenchymal intera...
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