Article
CD8+HLA-DR+ T cells are increased in patients with severe aplastic anemia.
Molecular medicine reports - 1 Sept 2014
Xing Limin, Liu Chunyan, Fu Rong, Wang Huaquan, Wang Jun, Liu Xiao, Feng Le, Li Lijuan, Liu Hui, Wang Honglei, Zhang Tian, Shao Zonghong
Abstract excerpt
The aim of the present study was to investigate the number and function of CD8+HLA-DR+ cells, which are considered to be activated cytotoxic T lymphocytes (CTLs), in peripheral blood to further examine the pathogenesis of severe aplastic anemia (SAA). Thirty-eight patients with SAA were included in the present study. Patients were screened for paroxysmal nocturnal hemoglobinuria by flow cytometry using anti-CD55...
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