Article
Identification of a SecM segment required for export-coupled release from elongation arrest.
FEBS letters - 25 Aug 2014
Nakamori Kenta, Chiba Shinobu, Ito Koreaki
Abstract excerpt
SecM in Escherichia coli has two functionally crucial regions. The arrest motif near the C-terminus interacts with the ribosomal exit tunnel to arrest its own translational elongation. The signal sequence at the N-terminus directs the SecM nascent polypeptide to the Sec-mediated export pathway to release the arrested state of translation. Here, we addressed the importance of the central region of SecM....
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