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Article

Cerebral microemboli increase β-amyloid protein deposition, MMP-9, and GFAP expression in the Alzheimer`s model of APP/PS1 double transgenic mice.

Current neurovascular research - 1 Jan 2014

Ning Min, Wu Yiying, Ni Xiushi, Zhao Yanling, Ling Rujing

Abstract excerpt

We investigated the effects of cerebral arterial microemboli on amyloid β protein (Aβ) deposition in the hippocampal region of amyloid precursor protein/presenilin 1 (APP/PS1) double transgenic mice and evaluated the role of cerebral arterial microemboli in Alzheimer's disease (AD) pathogenesis. The mice were divided into a wild-type sham surgery group (n = 15), a wild-type coupled with microemboli group (n =15),...

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Share to Amyloid beta-Peptides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24962158
DOI: 10.2174/1567202611666140606104132

Genes

GFAP
APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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