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Article

Novel cysteine-centered sulfur metabolic pathway in the thermotolerant methylotrophic yeast Hansenula polymorpha.

PloS one - 1 Jan 2014

Sohn Min Jeong, Yoo Su Jin, Oh Doo-Byoung, Kwon Ohsuk, Lee Sang Yup, Sibirny Andriy A, Kang Hyun Ah

Abstract excerpt

In yeast and filamentous fungi, sulfide can be condensed either with O-acetylhomoserine to generate homocysteine, the precursor of methionine, or with O-acetylserine to directly generate cysteine. The resulting homocysteine and cysteine can be interconverted through transsulfuration pathway. Here, we systematically analyzed the sulfur metabolic pathway of the thermotolerant methylotrophic yeast Hansenula...

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Identifiers

PMID: 24959887
DOI: 10.1371/journal.pone.0100725
PMCID: PMC4069077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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