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Article

Genome-wide association interaction analysis for Alzheimer's disease

28 May 2014

Abstract excerpt

We propose a minimal protocol for exhaustive genome-wide association interaction analysis that involves screening for epistasis over large-scale genomic data combining strengths of different methods and statistical tools. The different steps of this protocol are illustrated on a real-life data application for Alzheimer's disease (AD) (2259 patients and 6017 controls from France). Particularly, in the exhaustive...

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PMID: 24958192
DOI: 10.1016/j.neurobiolaging.2014.05.014

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