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Article

Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates.

RNA (New York, N.Y.) - 1 Aug 2014

Somme Jonathan, Van Laer Bart, Roovers Martine, Steyaert Jan, Versées Wim, Droogmans Louis

Abstract excerpt

The 2'-O-methylation of the nucleoside at position 32 of tRNA is found in organisms belonging to the three domains of life. Unrelated enzymes catalyzing this modification in Bacteria (TrmJ) and Eukarya (Trm7) have already been identified, but until now, no information is available for the archaeal enzyme. In this work we have identified the methyltransferase of the archaeon Sulfolobus acidocaldarius responsible...

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Identifiers

PMID: 24951554
DOI: 10.1261/rna.044503.114
PMCID: PMC4105751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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