Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Higher frequency of C.3435 of the ABCB1 gene in patients with tramadol dependence disorder.

The American journal of drug and alcohol abuse - 1 Jul 2014

Enabah Dalia, El Baz Heba, Moselhy Hamdy

Abstract excerpt

BACKGROUND: Polymorphic variation at the ABCB1 gene has been shown to affect the pharmacodynamics and kinetics of various drugs. AIM: This study aimed to determine the frequency of occurrence of Single Nucleotide Polymorphism (SNP) in position A118G OPRM1 (rs1799971) gene and C.3435 (rs1045642) gene in tramadol users in comparison with normal controls. METHODS: This was a cross sectional case-control outpatient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adolescent

Share to ATP Binding Cassette Transporter, Subfamily B

Share to Case-Control Studies

Share to Cross-Sectional Studies

Share to Gene Frequency

Share to Opioid-Related Disorders

Share to Receptors, Opioid, mu

Share to Young Adult

Source

Identifiers

PMID: 24950410
DOI: 10.3109/00952990.2014.925468

Genes

ABCB1
OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Higher frequency of C.3435 of the ABCB1 gene in patients with tramadol dependence disorder.PMID 24950410Read ↗

Association of the OPRM1 variant rs1799971 (A118G) and clinical manifestations in tramadol poisoned patients: a cross-sectional study.Semantic proximity Read ↗

Association between ABCB1 C3435T polymorphism and increased risk of cannabis dependence.Semantic proximity Read ↗

Pharmacokinetics of tramadol is affected by MDR1 polymorphism C3435T.Semantic proximity Read ↗

Consequences of the 118A&gt;G polymorphism in the OPRM1 gene: translation from bench to bedside?Semantic proximity Read ↗

Gene polymorphisms of OPRM1 A118G and ABCB1 C3435T may influence opioid requirements in Chinese patients with cancer pain.Semantic proximity Read ↗

Pilot study examining the frequency of several gene polymorphisms involved in morphine pharmacodynamics and pharmacokinetics in a morbidly obese population.Semantic proximity Read ↗

A118G mu opioid receptor polymorphism among drug addicts in Malaysia.Semantic proximity Read ↗

Pharmacogenomics of the human µ-opioid receptor.Semantic proximity Read ↗

Association of µ-opioid receptor (OPRM1) gene polymorphism with response to naltrexone in alcohol dependence: a systematic review and meta-analysis.Semantic proximity Read ↗

Haplotype-Based Association and In Silico Studies of OPRM1 Gene Variants with Susceptibility to Opioid Dependence Among Addicted Iranians Undergoing Methadone Treatment.Semantic proximity Read ↗

Allele frequency and genotype distribution of the opioid receptor μ-1 (OPRM1) A118G polymorphism in the Western Saudi population.Semantic proximity Read ↗

Association of Single-Nucleotide Polymorhism C3435T in the ABCB1 Gene with Opioid Sensitivity in Treatment of Postoperative Pain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.