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Article

Amiloride and SN-6 suppress audiogenic seizure susceptibility in genetically epilepsy-prone rats.

CNS neuroscience & therapeutics - 1 Sept 2014

Quansah Hillary, N'Gouemo Prosper

Abstract excerpt

AIMS: We have recently reported that amiloride, a potent and nonselective blocker of acid-sensing ion channels, prevents the development of pilocarpine-induced seizures and status epilepticus. Amiloride is also known to suppress the activity of Na(+) /Ca(2+) and Na(+) /H(+) exchangers that have b...

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Identifiers

PMID: 24948133
DOI: 10.1111/cns.12296
PMCID: PMC4461064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24948133-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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