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Article

Transplanted perivascular adipose tissue accelerates injury-induced neointimal hyperplasia: role of monocyte chemoattractant protein-1.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2014

Manka David, Chatterjee Tapan K, Stoll Lynn L, Basford Joshua E, Konaniah Eddy S, Srinivasan Ramprasad, Bogdanov Vladimir Y, Tang Yaoliang, Blomkalns Andra L, Hui David Y, Weintraub Neal L

Abstract excerpt

OBJECTIVE: Perivascular adipose tissue (PVAT) expands during obesity, is highly inflamed, and correlates with coronary plaque burden and increased cardiovascular risk. We tested the hypothesis that PVAT contributes to the vascular response to wire injury and investigated the underlying mechanisms. APPROACH AND RESULTS: We transplanted thoracic aortic PVAT from donor mice fed a high-fat diet to the carotid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24947528
DOI: 10.1161/ATVBAHA.114.303983
PMCID: PMC4103955

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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