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Article

Role of Perivascular Adipose Tissue in Vein Remodeling.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2025

Kruit Nicky, Sluiter Thijs J, de Vries Margreet R

Abstract excerpt

Perivascular adipose tissue (PVAT) plays a crucial, yet underexplored, role in vein remodeling, which occurs after bypass surgery using a venous graft or creation of arteriovenous fistulae for hemodialysis access. PVAT exhibits significant heterogeneity in phenotype and tissue composition depending on the vascular bed, as well as its anatomic location within the vasculature. Through the excretion of adipokines,...

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Identifiers

PMID: 40079141
DOI: 10.1161/ATVBAHA.124.321692
PMCID: PMC12017597

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