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Article

Impact of Perivascular Adipose Tissue on Neointimal Formation Following Endovascular Placement.

Journal of cardiovascular translational research - 1 Aug 2024

Tesfamariam Belay

Abstract excerpt

Following the placement of endovascular implants, perivascular adipose tissue (PVAT) becomes an early sensor of vascular injury to which it responds by undergoing phenotypic changes characterized by reduction in the secretion of adipocyte-derived relaxing factors and a shift to a proinflammatory and pro-contractile state. Thus, activated PVAT loses its anti-inflammatory function, secretes proinflammatory...

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PMID: 38409474
DOI: 10.1007/s12265-024-10502-0

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