Article
Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding.
Circulation research - 27 Feb 2009
Chatterjee Tapan K, Stoll Lynn L, Denning Gerene M, Harrelson Allan, Blomkalns Andra L, Idelman Gila, Rothenberg Florence G, Neltner Bonnie, Romig-Martin Sara A, Dickson Eric W, Rudich Steven, Weintraub Neal L
Abstract excerpt
Adipose tissue depots originate from distinct precursor cells, are functionally diverse, and modulate disease processes in a depot-specific manner. However, the functional properties of perivascular adipocytes, and their influence on disease of the blood vessel wall, remain to be determined. We show that human coronary perivascular adipocytes exhibit a reduced state of adipocytic differentiation as compared with...
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